Microplate lids are used to cover plates to protect well contents from leakage, contamination, and evaporation during assay processing, incubation, or storage. Lids are available for a variety of plates, and in a variety of materials, many with specific applications, including storage, fluorescence assays, luminescence assays, microscopy, and cell culture.
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An ionizable cationic lipidoid has been used in the generation of LNPs LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce the expression of Hsp47 in activated NIH3T3 mouse liver fibroblasts and primary mouse hepatic stellate cells LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce CCl4-induced liver fibrosis in mice
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An ionizable cationic lipidoid has been used in the generation of LNPs LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce the expression of Hsp47 in activated NIH3T3 mouse liver fibroblasts and primary mouse hepatic stellate cells LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce CCl4-induced liver fibrosis in mice
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A cationic lipid has been used for transfection of DNA RNA and other negatively charged molecules into eukaryotic cells has been used in the composition of small unilamellar liposomes formulated as gene delivery vectors for gene therapy
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A multi-kinase inhibitor selectively inhibits MET VEGFR2 Axl and Mer (IC50s 3 15 5.8 and 0.6 nM respectively) over serine/threonine kinases for which it has no activity but does inhibit 28 additional RTKs (IC50s 3-54 nM) and additional kinases by greater than 70 at 1 UM inhibits the proliferation of SNU-5 cells (IC50 98.9 nM) and HUVECs (IC50 10.4 nM) reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg increases the number of peripheral B cells and CD4 T cells and decreases the number of peripheral myeloid cells in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg
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An antagonist of NR2B subunit-containing NMDA receptors (Ki 72 nM) selective for NR2B subunit-containing NMDA receptors over those containing NR2A subunits (IC50s 47 and 10000 nM respectively) reduces carrageenan-induced hyperalgesia in rats (ED50 5.5 mg/kg) reduces dopaminergic neuron loss in the rat substantia nigra pars compacta and improves measures of ipsilateral curling ipsilateral head positioning and beam walking in a rat model of 6-OHDA-induced Parkinsons disease at 10 mg/kg
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